MOLECULAR BIOPHYSICS

Lines of activities:

  • Molecular Mechanisms of Action;
  • Possibility of Encapsulation;
  • Controlled Release of Complexes Formulated by Drugs and Proteins;
  • Structural and Dynamic Properties of Lipids and Proteins.
  • The Center for Molecular Biophysics Research consists in detecting sites of interaction of various signaling molecules with drugs and biomolecules; characterize these sites from the standpoint of structural and kinetic; investigate conditions that modulate interactions, correlating structure and kinetics with functional effects. We have obtained results on the elucidation of the molecular mechanisms of interaction of drugs with their targets in subcellular systems: biomembranes, soluble proteins and model systems. The potential use of nanoparticles for protein transport and controlled release of drugs from a living is great. Due to the small size and high magnetization, magnetic nanoparticles can be used to monitor and influence cellular processes. Various synthesis methods of magnetic particles have been developed, but detection, encapsulation and functionalization of those particles by biologically active molecules has been a challenge. Looking encapsulating magnetic particles with proteins and biomembranes to control connection and release of drugs. These activities are developed in the. Laboratory of Spectroscopy of Biomolecules.